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MARTINDALE'S
THE "VIRTUAL" - PHARMACY, PHARMACOLOGY & TOXICOLOGY CENTER PHARMACOLOGY & CLINICAL PHARMACOLGY |
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US/Pacific: Friday, May 16, 2008
Sydney, Australia: Saturday, May 17, 2008 File Download Time Calculator Author, E-Mail, Privacy Policy & Disclaimer |
INTRODUCTION TO THE PRINCIPLES AND PRACTICE OF CLINICAL RESEARCH (REAL PLAYER) Multimedia Introduction to the Principles and Practice of Clinical Research Course (Text, Images, Videos/Movies & Audio/Sound) Introduction to the Principles and Practice of Clinical Research (IPPCR)
Ethical Issues in Human Subjects Research; Monitoring Patient Oriented Research and Regulatory Issues; Preparing and Funding a Clinical Research Study..." PRINCIPLES OF CLINICAL PHARMACOLOGY (REAL PLAYER) - Warren Grant Magnuson Clinical Center, National Institutes of Health (NIH) Multimedia Clinical Pharmacology Course (Text, Images, Videos/Movies & Audio/Sound). Principles of Clinical Pharmacology Course is
Drug absorption and bioavailability; Effects of liver disease on pharmacokinetics; Population pharmacokinetics; etc..."
Equilibrative and concentrative transport; etc..."
Physiological and laboratory markers of drug effect; etc..."
Drug therapy in the elderly; etc..."
Animal scale up and Phase I studies; Pharmacokinetics of biotechnology products and large molecules; etc..." Medical Pharmacology
MEDICAL PHARMACOLGY - T.L. Pazdernik, L. Kerecsen & T. Kerecsen; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center Multimedia Medical Pharmacology Lectures (Text & Images). Medical Pharmacology Subject Categories include:
Pharmacology of the Autonomic Nervous System; Cardiovascular and Renal Pharmacology; Pharmacology of the Central Nervous System; Blood and Endocrine Pharmacology; Cardiovascular Pharmacology; etc..." MEDICAL BIOCHEMISTRY & PHARMACOLOGY - M.G. Marinus, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School Multimedia Medical Biochemistry & Pharmacology Lectures (Text & Images). Medical Pharmacology Lectures include:
Antifolates; Drugs Interfering with Nucleic Acid Synthesis
Agents Affecting Polymerization; DNA Repair; Agents reacting covalently with DNA; Agents which intercalate into DNA; Topoisomerase inhibitors and other Agents; etc..." Drugs Affecting Cell Wall/Membrane; etc. Generic Names & Trade Names Drug Pronunciation BASIC GENERIC & TRADE NAMES DRUGS PRONUNCIATION & CHEMICAL STRUCTURES - Department of Medicinal Chemistry, College of Pharmacy, University of Michigan Multimedia Basic Generic Names & Trade Names Drug Pronunciation & Chemical Structures (Text, Images & Audio/Sound). For more information see Medicinal Chemistry Courses; Medicinal Chemistry; Department of Medicinal Chemistry or the College of Pharmacy Cellular Physiology & Pharmacology
PHARMABASE - BioCurrents Resource Center, Marine Biological Laboratory, Woods Hole, Mass Multimedia Cellular Physiology & Pharmacology Database & Teaching Modules (Text & Images). Pharmbase
Metabolism; Intracellular Messengers; Cell Signaling; Cell Area; Disease/Tissue; etc..." |
FOR ANIMAL ANATOMY ATLASES, CASES, COURSES, DATABASES, JOURNALS, TEXTBOOKS, TUTORIALS, VIDEOS, ETC. SEE THE VETERINARY CENTER CARDIOVASCULAR PHARMACOLOGY
HyperHeart
THE HEALTHY HEART (FLASH) - B.H. Lewis, Division Of Cardiology, Department of Medicine, College of Physicians & Surgeons, Columbia University Medical Center, Columbia University and the Columbia Center for New Media Teaching and Learning, Columbia University Multimedia Heart Teaching Modules (Text, Images, Simulations & Audio/Sound). The Healthy Heart
CARDIOLOGY (FLASH & QUICKTIME) - Cardiology Site, A.S.M. Systems, Inc. Multimedia Heart Teaching Modules (Text, Images, Videos/Movies & Audio/Sound). Cardiology serves
3D HUMAN HEART STUCTURE & DYNAMICS - Elizabeth Cherry & Flavio Fento, The Virtual Heart, Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University Multimedia Heart Teaching Modules (Text & Images). The Human Heart is
EXCITABLE MEDIA AND CARDIAC DYNAMICS (JAVA APPLETS) - Elizabeth Cherry & Flavio Fento, The Virtual Heart, Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University Multimedia Arrhythmia & Cardiac Electrophysiology Teaching Modules (Text, Images, Applets, Calculators & Videos/Movies). Arrhythmia & Cardiac Electrophysiology Calculators & Applets Categories & Subcategories include:
Action Potential Duration (APD) Restitution; etc..."
2D Dynamics: Initiation, Propagation, Conduction Blocks and Spiral Waves in 2D; etc.
Hudgkin-Huxley Model Calculator
Heart Models (Ionic Models-SinoAtrial): Zhang-Holden-Kodama-Honjo-Lei-Varghese-Boyett Rabbit Periphery Sinoatrial Cell Model Zhang-Holden-Kodama-Honjo-Lei-Varghese-Boyett Rabbit Periphery Sinoatrial Cell Model Calculator
Heart Models (Ionic Models-Atrial): Nygren-Firek-Clark-Lindblad-Clark-Giles Model for Human Atrial Cells Nygren-Firek-Clark-Lindblad-Clark-Giles Model for Human Atrial Cells Calculator
Heart Models (Ionic Models-Ventrical): Tusscher-Noble-Noble-Panfilov Human Ventricular Cell Model Tusscher-Noble-Noble-Panfilov Human Ventricular Cell Model Calculator
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Cardiovascular Pharmacology Lectures include:
Calcium Channel Blockers; Cardiac AntiArrythmic Drugs; Diuretics; Drugs Used in the Treatment of Congestive Heart Failure I Digitalis; Introduction to Autonomic Pharmacology; The Rational Use of Drugs; etc..." Cardiovascular & Cardiopulmonary Physiological Model
Closed Loop Cardiopulmonary System with Selectable Interventions is
Gao Autoregulatory Model
Cardiovascular System - Hemodynamics: Thick Wall Cylinder Tangential Stress Model - Author: Max Neal Thick Wall Cylinder Tangential Stress Model
Integrative Physiology: Cardiac Output Estimation in Reference Human Model - Author: Maxwell Neal Cardiac Output Estimation in Reference Human Model is a
Integrative Physiology: Cardiopulmonary Mechanics Model - Author: Maxwell Neal Cardiopulmonary Mechanics Model is
Integrative Physiology: Highly-integrated Human with Interventions Model - Author: Maxwell Neal Highly-integrated Human with Interventions Model is
DERMATOLOGICAL PHARMACOLOGY
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DRUG TARGET DATA, DRUG CHEMICAL STRUCTURES,
Related Centers
FOR MORE THAN 200 RELATED DATABASES INCLUDING CHMICAL COMPUNDS, REACTIONS, LIPIDS, MOLECULAR MODELING, ETC. SEE CHEMICAL & BIOCHEMICAL DATABASES FOR MORE THAN 300 RELATED DATABASES INCLUDING PROTENS, AMIOIN ACIDS, PEPTIDES ETC. SEE TH BIOSCIENCE & BIOTECHNOLOGY CENTER
DrugBank is
Drug Metabolism
DRUG METABOLISM - Division of Drug Metabolism, American Society for Pharmacology and Experimental Therapeutics (ASPET) Multimedia Drug Metabolism Teaching Modules & Databases (Text & Images). Drug Metabolism Subject Categories include:
Flavin Monooxygenase; Glucuronyltransferases; Glutathione-S-transferases; N-acetyltransferases; Sulfotransferases; P-glycoprotein..." Drug Metabolism Databases DRUG INTERACTION TABLE - CYTOCHROME 450 SYSTEM - Division of Clinical Pharmacology, Department of Medicine, Indiana University Multimedia Drug Interaction Table: Cytochrome P450 System Database (Text & Images). Drug Interaction Table: Cytochrome P450 System Database
Anti-epileptics; NSAID; Oral Hypoglycemic Agents; Angiotensin II Blockers; Sulfonylureas; Beta Blockers; Antidepressants; Antipsychotics; Anesthetics; Macrolide Antibiotics; Benzodiazepines; Immune Modulators; HIV Antivirals; Calcium Channel Blockers; etc..."
PDSP Ki DATABASE - B. Roth, Department of Biochemistry, School of Medicine, Case Western Reserve University Multimedia Database (Text & Images). PDSP Ki Database is
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Development Therapeutics Program Database includes:
Basic Chemical Data; Assays of Molecular Targets; Browse Cancer Screening Data; Bulk Data Download; Search In Vivo Screening Data; Search Yeast Screening Data; AIDS Screening Data; etc..." OSIRIS PROPERTY EXPLORER - B. Bart & R. Müller, Switzerland Multimedia Chemical Structures Database (Text, Images & 3D Modeling). Available in English & German/Deutsch. OSIRIS Property Explorer
cLogP Prediction; Solubility Prediction; Molecular Weights; Fragment-based Drug-Likeness Prediction; Overall Drug-Likeness Score, etc..." OSIRIS PROPERTY EXPLORER (JAVA APPLET) - ChemExper sprl, Belgium Multimedia Chemical Structures Database (Text, Images & 3D Modeling). OSIRIS Property Explorer
THE DUNDEE PRODRG SERVER - D. van Aalten, Department of Biochemistry, University of Dundee, Dundee, Scotland, U.K. Multimedia Molecular Topologies for X-ray Refinement, MD Drug Design, Docking Database (Text, Images & 3D Modeling). Dundee Prodrg Server
Drug Likeness & Molecular Property Prediction
Drug-Likeness and Molecular Property Prediction Database
CALCULATION OF MOLECULAR PROPERTIES - Author: P. Ertl, Novartis Pharma AG, Basel, Switzerland, and Hosted by Molinspiration Cheminformatics, Bratislava, Slovak Republic Calculation of Molecular
Single Nucleotide Poloymorphism
Single Nucleotide Poloymorphism (dbSNP)
New Batches; Method; Population; Publication..." GENESNPS - Genome Center, University of Utah Multimedia Database (Text & Images). GeneSNPs
JAPANESE SINGLE NUCLEOTIDE POLYMORPHISMS (JSNP) DATABASE - GDB Japan Node JST, Japan Multimedia Single Nucleotide Poloymorphism Database (Text & Images). Single Nucleotide Polymorphisms (SNPs)
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Haplotypes
"...With the exception of the sex cells, the chromosomes in human cells occur in pairs. One member of each chromosome pair is inherited from a person's father; the other member of the pair is inherited from that person's mother. But chromosomes do not pass from each generation to the next as identical copies...." ION CHANNELS, MOLECULAR MOVEMENTS, PROTEIN FOLD RECOGNITION & RECEPTORS
Guide to Receptors and Channels
Transmitter-Gated Channels; Ion Channels; Catalytic Receptors; Nuclear Receptors; Cell-Surface Transmitter Transporters; Enzymes; etc.. ION CHANNELS, TRANSMITTERS, RECEPTORS & DISEASE - Department of Neurology, Washington University School of Medicine, St Louis Multimedia Ion Channel, Transmitters, Receptor & Disease Database (Text & Images). Ion Channel, Transmitters, Receptor & Disease Subject Categories include:
Gap junctions; Long QT Syndromes; Potassium; K+/H+ ATPase; Sodium; Sodium/Hydrogen Exchangers; Toxins..." Transmitters/Receptors; etc. IUPHAR COMPENDIUM OF VOLTAGE-GATED ION CHANNELS - International Union of Pharmacology (IUPHAR) Multimedia Voltage-gated Ion Channels Database (Text & Images). VIUPHAR Compendium of Voltage-gated Ion Channels Database Subject Categories include:
Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels; Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels; Nomenclature and Structure-Function Relationships of Transient Receptor Potential Channels; Nomenclature and Structure-Function Relationships of CatSper and Two-Pore Channels; etc..." Molecular Movements Databases Molecular Movements Databases with Text, Images & Videos/Movies MOLECULAR MOVEMENTS DATABASE - N. Echols, Bioinformatics Web Server, Department of Molecular Biophysics and Biochemistry, Yale University Multimedia Molecular Movements Database (Text, Images & Videos/Movies). Molecular Movements Database
Protein Fold Recognition
3D-PSSM & PHYRE - Structural Bioinformatics Group, Imperial College Center Bioinformatics, U.K. Multimedia Protein Fold Recognition Databases (Text, Images & Videos & Videos/Movies). 3D-PSSM & PHYRE
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Guide to Receptors and Channels
Transmitter-Gated Channels; Ion Channels; Catalytic Receptors; Nuclear Receptors; Cell-Surface Transmitter Transporters; Enzymes; etc.. RECEPTOR NOMENCLATURE AND DRUG CLASSIFFICATION - International Union of Pharmacology (IUPHAR) Multimedia Receptor Nomenclature and Drug Classification Database (Text & Images). Receptor Nomenclature and Drug Classification Subject Categories include:
IUPHAR Receptor Code; IUPHAR Receptor List & Terms and Symbols..." RECEPTOR BINDING - J. Deupree, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center (UNMC), University of Nebraska Multimedia Receptor Binding Teaching Modules (Text & Images). For more information see the Department of Pharmacology and Experimental Neuroscience GPCR NATURAL VARIANTS DATABASE - Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research (LACDR), University of Leiden, The Netherlands Multimedia GPCR Natural Variants Database (Text & Images). GPCR Natural Variants Database
GPCRDP: G PROTEIN-COUPLED RECEPTORS (GPCRs) DATABASE - Molecular Class-Specific Information System (MCSIS) project, The Netherlands Multimedia G protein-coupled receptors (GPCRs) Database (Text & Images). For more information see Molecular Class-Specific Information System (MCSIS) project OLFACTORY RECEPTOR DATABASE (ORDB) - Sense Lab Project, Shepherd Lab., Yale University School of Medicine, Yale University Multimedia Olfactory Receptors Database (Text & Images). Olfactory Receptors Database
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FOR CHEMISTRY CALCULATOR SEE THE CALCULATORS ON-LINE CENTER: CHEMISTRY CALCULATORS CENTER
NEUROPSYCHOPHARMACOLOGY
Neuropsychopharmacology
Clinical Analysis of Methods; Transitter Systems: Amino Acids, Acetylcholine, Amines; Central Norepinephrine Neurons and Behavior; Gene Targeting Approaches to Serotonin Receptors; Indoleamines: The Role of Serotonin in Clinical Disorders; Peptides; Introduction to Clinical Neuropsychopharmacology; etc..."
Cytology and Circuitry Excitatory Amino Acid Neurotransmission Molecular Biology of the Dopamine Receptor Subtypes Dopamine Receptors: Clinical Correlates Serotonin and Behavior Introduction to Clinical Neuropsychopharmacology Neuropeptide Alterations in Mood Disorders The Role of Serotonin in Schizophrenia Neuropsychopharmacology: The Fifth Generation of Progress Sections include:
Emerging Methods In Molecular Biology And Genetics; Emerging Imaging Technologies And Their Application To Psychiatric Research; Drug Discovery And Evaluation; Disorders Of Development; Schizophrenia And Related Disorders; Anxiety And Stress Disorders; etc..."
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PharmGKB
PHARMACOKINETICS & BIOPHARMACEUTICS
Pharmacokinetics
Pharmacological Response; IV Bolus; IV Infusion; Biopharmaceutical factors; Oral Dosing; Bioavailability; Clearance; Dosage; Multicompartment model; Protein Binding; Non-linear kinetics..." Pharmacokinetics & Biopharmaceutics
Pharmacokinetics & Biopharmaceutics Chapters include:
Analysis of Urine Data; Intravenous Infusion; Routes of Drug Administration; Pharmacokinetics of Oral Administration; Bioavailability Studies; Physiological Factors Affecting Oral Absorption; Physical-Chemical Factors Affecting Oral Absorption; Multiple IV Bolus Dose Administration; Multiple Oral Dose Administration; Routes of Excretion; etc..." PHARMACOKINETICS AND BIOPHARMACEUTICS (PHAR 7632/7633)- D. Bourne, Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Multimedia Pharmacokinetics & Biopharmaceutics Course (Text, Images & Calculators). Pharmacokinetics & Biopharmaceutics Chapters include:
Multiple IV bolus dose administration; Multiple oral dose administration; Drug metabolism; Drug distribution; Multi-compartmental pharmacokinetic models; Non-linear pharmacokinetic models; Clinical applications of pharmacokinetics; Optimal sampling; etc..." PHARMACOMETRICS
Pharmacometrics
Population Analysis; Estimation Methods; Good Modeling Practices (GMP)..."
PHARMACOTHERAPEUTICS
NEUROLOGY PHARMACOTHERAPEUTICS: PHA 4220 - P.M. Woster, Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, Wayne State University Multimedia Neurology Pharmacotherapeutics Teaching Modules (Text & Images). For more information see The Woster Module Medchem Page; Patrick M. Woster'S Home Page; Department of Pharmaceutical Sciences or the College of Pharmacy and Allied Health Professions
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The Radiation Internal Dose Information Center (RIDIC) has been
MEDICAL PROCEDURE RADIATION DOSE CALCULATOR AND CONSENT LANGUAGE GENERATOR - M. Stabin, Vanderbilt University & RADAR Medical Procedure Radiation Dose Calculator and Consent Language Generator
Skull Radiographic; CT Head Scan; Abdominal X-ray..."
Co-57 Cyanocobalamin, IV No Carrier; Cr-51 Sodium Chromate RBC's etc..." RADIATION DOSE TO THE BREAST FROM MAMMOGRAPHY - CALCULATOR - R.E. Reiman, General Secretary, DUMC Radiation Safety Committee, Duke University Medical Center, and hosted by the Occupational & Environmental Safety Office (OESO), Duke University Radiation Dose to the Breast from Mammography Calculator (Radiation Dose Calculator)
Glandular Fraction; Skin Entrance Exposure; Target/Filtration Combination
RADIATION DOSE TO THE SKIN FROM VARIOUS BETA EMITTERS CALCULATOR - R.E. Reiman, General Secretary, DUMC Radiation Safety Committee, Duke University Medical Center, and hosted by the Occupational & Environmental Safety Office (OESO), Duke University Radiation Dose to the Skin From Various Beta Emitters Calculator (Radiation Dose Calculator)
Iodine 31, Cobalt 60 or Cesium 137);
RADIATION EFFECTIVE DOSE FROM CT SCANS CALCULATOR - R.E. Reiman, General Secretary, DUMC Radiation Safety Committee, Duke University Medical Center, and hosted by the Occupational & Environmental Safety Office (OESO), Duke University Radiation Effective Dose From CT Scans Calculator (Radiation Dose Calculator)
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Veterinary Clinical Pharmacology Case Studies include:
VETERINARY CLINICAL PHARMACOLOGY (VM8784) - J.R. Wilcke, Clinical Pharmacology, Virginia-Maryland Regional College of Veterinary Medicine Multimedia Veterinary Clinical Pharmacology Course (Text & Images). Veterinary Clinical Pharmacology Chapters & Subchapters include:
Pharmacokinetic Models; Pharmacokinetic Constants; Therapeutic Drug monitoring: Aminoglycosides, Digoxin, etc..."
Antimicrobial Tables; etc..."
Systemic Effects of Glucocorticoid; Glucocorticoids as Drugs; Glucocorticoid Replacement Therapy; etc..."
Pharmacokinetics; Dosing; Toxicity; etc..."
Vasodilators; Diuretics; etc..."
Central-acting antiemetics; etc.." |
FOR MORE THAN "400" STATISTICAL COURSES & CALCULATORS SEE THE CALCULATORS ON-LINE CENTER: STATISTICS CALCULATORS CENTER
SURFSTAT STATISTICS 101 (JAVA APPLETS) - K. Dear, National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia Multimedia Statistics Course (Text, Images, Calculators & Java Applets). Examples of Statistics Course Chapters, Subchapters, etc. include:
Continuous Data; Characteristics of a Distribution; Measures of Central Tendency; Measures of Variability; etc..."
The Scientific Method..."
Independence and Tree Models for Calculating Probabilities; Conditional Probabilities; Bayes' Theorem; Random Variables; Expected Values, Variances and Covariances of Random Variables; etc..."
Point estimation and interval estimation; Results from probability theory; Comparing means of two continuous variables; Inference for count data; etc..." Java Applets; Exercises with Solutions; Glossary; etc. VASSARSTATS: STATISTICAL COMPUTATION - R. Lowry, Department of Psychology, Vassar College, Poughkeepsie, N.Y. Multimedia Statistics Course (Text, Images, Calculators & Java Applets). VERY VERY VERY...EXTENSIVE. VassarStats: Statistical Computation
Randomizer Calculator; Simple Graph Maker Calculator; etc..." Probabilities Calculators
Pascal (Negative Binomial) Probabilities Calculator; Backward Probability Template Calculator; etc..."
Poisson Distributions Calculator; Chi-Square Distributions Calculator; t-Distributions Calculator; Distributions of r Calculator; F-Distributions Calculator; etc..."
Kolmogorov-Smirnov One-Sample Test Calculator; etc..."
Significance of the Difference Between Two Correlated Proportions Calculator; etc..."
Mann-Whitney Test Calculator; Wilcoxon Signed-Ranks Test Calculator; etc..." t-Tests & Procedures Calculators
t-Test for Independent or Correlated Samples Calculator; etc..." Examples of Calculators CALCULATORS FOR PHARMACOKINETICS & BIOPHARMACEUTICS - D.W.A. Bourne, College of Pharmacy, University of Oklahoma For more information see A First Course in Pharmacokinetics and Biopharmaceutics; David W.A. Bourne's Home Page or the College of Pharmacy
IV Bolus One Compartment Linear Model Calculator INPUT Values include:
Elimination Rate Constant; Time since IV Dose..." Cp Average Calculator Cp Average Calculator INPUT Values include:
Intravenous Administration: Two compartment Microconstants to Macroconstants Calculator Intravenous Administration: Two compartment Microconstants to Macroconstants Calculator INPUT Values include:
Dosing Approaches: Saturable Elimination Determine Km and Vm Calculator Dosing Approaches: Saturable Elimination Determine Km and Vm Calculator INPUT Values include:
Saturable Elimination Average Concentration Calculator Saturable Elimination Average Concentration Calculator INPUT Values include:
GraphPad Software
McNemar's Test to Analyze a Matched Case-control Study Calculator
Number Needed to Treat (NNT) Calculator - How Effective is a Clinical Treatment? Number Needed to Treat Calculator (NNT Calculator) INPUT Values include:
Desired Confidence Level..." Post Test Calculator After Two-way (or other) Analysis of Variance (ANOVA) Post Test Calculator After Two-way (or other) Analysis of Variance (ANOVA)
Randomly Assign Subjects to Treatment Groups Calculator andomly Assign Subjects to Treatment Groups Calculator INPUT Values include:
Compute ECanything from EC50 Calculator Compute ECanything from EC50 Calculator INPUT Values include:
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